Words similar to hla-dqa
Example sentences for: hla-dqa
How can you use “hla-dqa” in a sentence? Here are some example sentences to help you improve your vocabulary:
5a, lanes 7-8) competes very poorly against the HLA-DQA1*0101 Y-box probe.
Finally, DEK binds differentially to specific Y-box sequences found in HLA-DQA1(*0101 and *0501 alleles) and HLA-DRA , consistent with observations of DQA1 gene-specific cell-surface expression [ 36 ] and allele-specific promoter activity [ 33 ] . The specificity of rDEK binding to these and other, related Y-box sequences (including HLA-DQB and HLA-DRB alleles associated with the DR4 haplotype) may correlate with a predisposition to autoim-mune disease seen with certain HLA haplotypes.
Divergence of the HLA-DQA1*0501 Y-box sequence at one position within the required NF-Y binding site reduces its ability to compete with the DRA Y-box probe (Fig.
Having established that DEK and NF-Y in nuclear extracts participate in the HLA-DQA1*0101 binding complex, we used recombinant full-length DEK (rDEK) to determine whether it alone can bind to Y-box motifs and to examine how gene- and allele-specific sequence polymorphisms alter its binding.
Both DEK and NF-Y participate in the HLA-DQA1Y-box binding complex