Example sentences for: hla-dqa

How can you use “hla-dqa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Divergence of the HLA-DQA1*0501 Y-box sequence at one position within the required NF-Y binding site reduces its ability to compete with the DRA Y-box probe (Fig.

  • The HLA-DQA1*0101 Y-box sequence does bind rDEK specifically, with unlabeled probe sequence competing successfully for binding (Fig.

  • The consensus ( HLA-DRA ) Y-box sequence differs from the HLA-DQA1*0101 Y box by a single nucleotide immediately 5' of the reverse CCAAT pentamer; this single-nucleotide polymorphism significantly changes the electrophoretic pattern (Fig.

  • HLA-DQA1*0101 oligonucleotide also competes poorly with the consensus Y-box probe for binding (Fig.

  • Finally, DEK binds differentially to specific Y-box sequences found in HLA-DQA1(*0101 and *0501 alleles) and HLA-DRA , consistent with observations of DQA1 gene-specific cell-surface expression [ 36 ] and allele-specific promoter activity [ 33 ] . The specificity of rDEK binding to these and other, related Y-box sequences (including HLA-DQB and HLA-DRB alleles associated with the DR4 haplotype) may correlate with a predisposition to autoim-mune disease seen with certain HLA haplotypes.


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