Example sentences for: hla-dr

How can you use “hla-dr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 2Ashows that large quantities of HLA-DR molecules are secreted by precursors of dendritic cells (DC) among epithelial cells in the mid parabasal layer (arrows).

  • Two additional genes, HLA-DR alpha and SNRP-B, that were also obtained using the two protocols, were confirmed by northern blotting (Fig 2A).

  • The T cells entering intermediate layers show a loss of HLA-DR expression and commit suicide with apoptotic fragmentation under the assistance of mature DC.

  • T helper epitopes have become common components of synthetic vaccine constructs due to their ability to provide immunological help for both humoral and cell-mediated responses [ 11 14 15 16 ] . T cell epitopes that can induce helper activity by binding to a wide range of HLA-DR alleles have been developed by a number of investigators using various antigen systems [ 17 18 19 ] . T cell epitopes that have the property of binding across a wide range of HLA-DR haplotypes are necessary for the construction of synthetic vaccines that would be useful in the human population as a whole.

  • Regarding part one, IFN-γ levels are elevated in the sera of HIV +patients [ 45 ] . Serum levels of both TNF-α and IFN-γ were markedly higher in HIV +patients over controls, but varied depending on the skin disease exhibited by the patient [ 46 ] . AIDS patients also showed elevated TNF-α levels in the plasma [ 47 ] . Studies of lymphocytes from aged donors showed increase serum levels of TNF-α and IFN-γ that correlate with upregulation of HLA-DR on CD3 +-lymphocytes [ 48 ] .


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