Words similar to hla-a
Example sentences for: hla-a
How can you use “hla-a” in a sentence? Here are some example sentences to help you improve your vocabulary:
Further, this implies that putative Ch6p alleles associated with CVID or IgGSD susceptibility occur on many HLA haplotypes that are common in Caucasians in central Alabama [ 10 ] and in Caucasians from a large national bone marrow donor program [ 14 ] . The present observations also confirm and extend the reports of association of HLA haplotype A*01-B*08 (or an extended haplotype containing A*01 and B*08) with heritable forms of immunoglobulin deficiency demonstrated in family-based analyses [ 3 6 19 20 21 22 ] . It is likely that a candidate gene(s) for CVID or IgGSD exists in the HLA class II region, [ 6 19 20 21 22 23 ] . Because the class II region is closer to the HLA-B locus than to the HLA-A locus, it is plausible that candidate gene(s) for CVID or IgGSD in the class II region are in greater linkage disequilibrium with HLA-B than HLA-A.
There were no other significant differences in HLA-A phenotype frequencies between these groups (Table 2).
A data set that included HLA-A and -B phenotypes in 240 index patients with either CVID or IgGSD and HLA-A and -B haplotypes in 195 of these 240 index patients was available.
We diagnosed CVID or IgGSD in first-degree or other relatives of 26 of 195 index patients for whom HLA-A and -B haplotypes had been ascertained.
Data from 1,321 apparently normal, unrelated Caucasian adult subjects from Alabama who had undergone HLA-A and -B phenotype analysis as part of paternity testing were used to estimate allele and gene frequencies [ 10 13 ] . HLA-A and -B haplotypes were determined in 751 unrelated Caucasian subjects from Alabama who had undergone testing to establish paternity [ 10 ] . Haplotypes were assessed from a child and his/her mother or father, and included in the data set.
Loading...