Example sentences for: hla

How can you use “hla” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Genetically, almost all patients have one of two predisposing HLA molecules, which determine the context in which their immune system encounters foreign antigens, including gluten proteins found in wheat and other cereals.

  • In each proband in whom a single A or B allele was detected by DNA-based typing, we verified the allele(s) and set phase to ascertain haplotypes of the proband using HFE and HLA analyses of appropriate family members.

  • For example, 1) in Type 1 diabetes mellitus, the bulk of both the linkage and association data implicate the HLA region and INS [22]; 2) for Type 2 diabetes mellitus, there are a number of findings in the literature where the association evidence appears to be consistent and compelling ( CAPN10 , KCNJ11 , and PPARG )—the data indicate that the same marker allele is significantly associated and has an effect size of similar direction and magnitude [22] (the linkage data are less congruent, probably due to power considerations); and 3) for age-related macular degeneration, at least five studies show highly significant association with the same CFH Y402H polymorphism [23–27] in a region strongly implicated by multiple linkage studies.

  • CVID and IgGSD are significantly associated with the HLA haplotypes A*01-B*08, A*02-B*44, A*03-B*07, A*03-B*14, A*31-B*40, and A*32-B*14.

  • Author 2 (LFB) contributed CVID and IgGSD index cases, case characterization, and HLA typing.


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