Words similar to hct

Example sentences for: hct

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Whereas all tab mutants tested were able to bypass cdc15Δ in the absence of HCT1 and two ( net1 tab 2-1and CDC14 TAB 6-1) were able to bypass cdc15Δ in the absence of either SIC1 or HCT1, four tab mutants ( tab1-1, tab3-1, TAB5-1, and TAB7-1 ) failed to bypass in the absence of SIC1 (Table 3).
hct1Δ sic1Δ cells are inviable, presumably due to their inability to extinguish Cdc28 activity in telophase [ 3 ] .
Cdc14 subsequently dephosphorylates (and thereby activates) proteins involved in Sic1 expression (Swi5) and C1b degradation (Hct1/Cdh1) [ 19 41 50 ] , thereby eliminating mitotic Cdk activity and promoting exit from mitosis.
In S. cerevisiae, a key event accompanying exit from mitosis is the inactivation of Clb/Cdc28 protein kinase achieved through degradation of Clb and accumulation of the Clb/Cdc28 inhibitor Sic1 (reviewed in [ 1 ] ). Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase and its substrate specific activator Hct1/Cdh1 are required for degradation of Clb2, the major mitotic cyclin in the budding yeast (reviewed in [ 2 ] ). Whereas hct1Δ and sic1Δ cells appear relatively normal,
Stein et al [ 29] have found that cytokines such as interleukin-2, interferon-γ and tumour necrosis factor-α were capable of decreasing the expression of MDR1 mRNA in the colon carcinoma cell lines HCT15 and HCT16.