Words similar to hck

Example sentences for: hck

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This approach has been successful in producing conditional forms of the Tec family PTK Bmx [ 22], and also the PTKs v-Src [ 23], Hck [ 24] and Abl [ 25], the serine/threonine kinases Raf [ 26] and Akt [ 27], and the dual specificity protein kinase MEK1 [ 23].
These data agree both with two-hybrid experiments and in vitro filter binding assays that have demonstrated specific binding of the proline-rich region near the amino-terminus of BTK and Tec to the SH3 domains of the Src family kinases Fyn, Lyn and Hck [ 22, 25, 26].
Although our original SH3 domain binding experiments suggested a specific interaction between Tec kinases and the Src kinases Fyn, Lyn and Hck, we have been able to observe both activation by and co-precipitation with other Src family kinases including Lck and Src in 293T cells (data not shown).
Because Fyn is expressed in T cells and Hck and Lyn are not, we pursued the connection between Rlk and the T cell-specific isoform p59 FynT.
GST fusions encoding the Rlk amino-terminal and SH3 domains or the amino-terminus alone (containing the cysteine string and proline-rich region) bound biotinylated GST fusions of the SH3 domains of Fyn, Hck, and Lyn, but not those of Src or Lck, despite the ability of these constructs to bind other proline rich sequences (Fig.