Example sentences for: hbas
How can you use “hbas” in a sentence? Here are some example sentences to help you improve your vocabulary:
They note that in a recent study, conducted by another group in western Kenya, protection against severe malaria by HbAS was only seen in children 2–16 months old, but that in that study, no analysis was presented that addressed the effect of age within that range.
The mechanism behind the high degree of resistance conferred by HbAS in severe and complicated malaria is still unknown, but recent observations have suggested the mechanism might involve an immune component.
In this month's PLoS Medicine , Thomas Williams and colleagues reason that the best way to test whether malaria protection by HbAS has a significant immune component is to see whether protection varies with age.
They suggest several mechanisms for how HbAS could accelerate immune acquisition; for example, immunity could be mediated by accelerated acquisition of antibodies to altered host antigens expressed on the parasite-infected red cell surface.
For accelerated malaria-specific immunity to be relevant to HbAS selection it would have to operate within a period of maximum risk for severe and fatal malaria.
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