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Example sentences for: hccr

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4B, co-expression of pGal4-hCCR4 with either pVP16-hCAF1 or pVP16-hPOP2 elicited a significant increase (> 35 fold) in pG4-TK-Luc expression, thus demonstrating association between hCCR4 and either hCAF1 or hPOP2.
The complete hCCR4 cDNA was obtained (KIAA1194 cDNA, Kazusa DNA Research Institute), and vectors were constructed to express hCCR4 fused to the DNA binding domain of the yeast GAL4 transcription factor (pGal4-hCCR4) (Fig.
Interestingly, we found that hCCR4 also binds to the second human yPOP2 paralog, hCAF1.
Interestingly, the putative hCCR4, mCCR4, dCCR4 and ceCCR4 proteins are much smaller than yCCR4.
This increase is dependent on the presence of the leucine-rich repeats within hCCR4, since deletion of four out of the five leucine-rich repeats -within pGal4-hCCR4(ΔLRR), see Materials and Methods- completely abolished the effect (Fig.