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Example sentences for: hcalif

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Several components of the yCCR4-associated complexes have already been identified in humans: two homologs of yPOP2 (named hCAF1 and hPOP2/hCALIF) [ 16 17 18 19 ] , and homologs of NOT proteins (named hNOT1, hNOT2, hNOT3, hNOT4) [ 19 ] . Moreover, interactions between these proteins were demonstrated [ 19 20 ] . Yet, at the present time there has been no report of a human protein that would be structurally and functionally close to yCCR4.
Two homologs of yPOP2 have been identified in mammals: the mouse/human CAF1 [ 11 16 17 33 ] and, more recently, the human homolog named hPOP2 or hCALIF [ 18 19 ] . Both mCAF1 [ 11 ] and hPOP2 [ 19 ] interact with yCCR4, and the yCCR4 LRR is essential for these interactions.