Words similar to hcaf

Example sentences for: hcaf

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Third, the ability of yCCR4 to bind mCAF1 and hPOP2 is conserved for the mammalian protein, since we could demonstrate, using two-hybrid assays and far-Western blot analyses, an in vivo and in vitro interaction between hCCR4 and hCAF1 or hPOP2/CALIF.
However, at variance with hPOP2, hCAF1 is not able to interact with hNOT1 (nor with hNOT3) [ 19 ] . This suggests that human cells may contain at least two complexes involving a CCR4/POP2 association, a CCR4-NOT-POP2 complex analogous to the CCR4-NOT yeast complex, and a still unknown CCR4-CAF1 containing complex.
Here we report the identification of nineteen yCCR4-like proteins in eukaryotes and show, by phylogenetic and genomic analyses, that they are grouped into four distinct families, one of which contains the yCCR4 orthologs : these orthologs, in animals, have conserved the yCCR4 leucine-rich repeat, and we show, using two-hybrid assays and far-Western experiments, that the human protein binds to the human yPOP2 homologs, i.e. hCAF1 and hPOP2, in a LRR-dependent manner.
Interaction of the human homolog of yCCR4 with hCAF1 and hPOP2/CALIF
m.nocturnin, had no effect when co-expressed with either pVP16-hCAF1 or pVP16-hPOP2 (Fig.