Words similar to hcar

Example sentences for: hcar

How can you use “hcar” in a sentence? Here are some example sentences to help you improve your vocabulary:

In an effort to facilitate gene transfer into primary lymphocytes, we and others [ 14 15 ] have employed different strategies to engineer transgenic mice that express the human adenoviral receptor, hCAR, on murine lymphocytes.
The development of newer recombinant adenoviruses containing elements for epichromosomal replication may alleviate limitations that prevent more stable in vivo expression in dividing lymphoid cells derived from hCAR transgenic mice.
An important consideration at the outset of these studies concerned the possibility that ectopic hCAR expression or adenoviral transduction might affect the normal development and/or function of T cells.
For this reason, we chose to use a truncated variant of hCAR to preclude possible signaling by this molecule [ 13 ] . As evidenced by the functional data reported herein, and those from previous reports [ 14 15 ] , there does not appear to be an adverse effect of either hCARΔcyt expression or adenoviral transduction on T cell activation, development or function.
For these experiments, we used line 13 DO11.hCARΔcyt Tg mice that have a bimodal distribution of hCAR expression to provide an internal control, "sham transfection" population.