Example sentences for: hcar

How can you use “hcar” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To further investigate the effects of adenoviral transduction on T cell biology, and to examine the possibility that hCAR expression (an Ig superfamily member of undetermined function) might alter the in vivo distribution of transduced T cells, we examined the tissue distribution of DO11.hCARΔcyt T cells following adoptive transfer into BALB/c recipients.

  • In agreement with previous studies using human CD2 mini-gene expression cassette [ 16 17 18 ] , the truncated hCAR transgene was expressed in all cells of the T cell lineage, and except for transgenic line 6 (hCARΔcyt.CD2.

  • Here we report the characterization of three new transgenic lines that express a cytoplasmic-tail truncated hCAR under control of hCD2 gene regulatory elements, and demonstrate their utility for gene transfer studies of primary T cells and thymocytes.

  • 6), in which there was expression on mature B cells as well as T cells, hCAR was not expressed by non-T cells.

  • In an effort to facilitate gene transfer into primary lymphocytes, we and others [ 14 15 ] have employed different strategies to engineer transgenic mice that express the human adenoviral receptor, hCAR, on murine lymphocytes.


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