Words similar to gtpases
Example sentences for: gtpases
How can you use “gtpases” in a sentence? Here are some example sentences to help you improve your vocabulary:
Amino acid substitutions in the N(T)KxD motif cause a drastic reduction in the affinity of Ras-related GTPases for guanine nucleotides [ 35 36 ] . When overexpressed in cultured cells, these mutant GTPases function as dominant-suppressors of their endogenous counterparts [ 26 27 31 ] , presumably because they can compete for interaction with effectors, exchange factors or docking proteins, but cannot cycle on and off membranes in a nucleotide-dependent manner.
This could occur by the release of limited effector molecules shared between the two GTPases, possibilities that are currently under investigation.
These posttranslational lipid modifications are essential for attachment of the GTPases to the cytosolic face of intracellular vesicles and/or to the cytosolic leaflet of the plasma membrane, thereby specifying subcellular targets for GTPase action(s).
Other domains with less significant E-values include domains that are associated with the Rho family of GTPases, the RhoGEF domain (1.
Further study of Rho and it's related GTPases and downstream effector molecules, will be important in elucidating mechanisms regulating the lymphocyte cytoskeleton and thus T cell function.
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