Words similar to gtpases
Example sentences for: gtpases
How can you use “gtpases” in a sentence? Here are some example sentences to help you improve your vocabulary:
FH proteins control rearrangements of the actin cytoskeleton and members of this family have been found to interact with Rho-GTPases.
Isoprenylation serves to target the GTPases to the proper organelle membrane, where their actions often relate to cytoskeletal dynamics and/or vesicle trafficking [20,42].
ADP-ribosylation of Rho proteins by C3 exoenzyme prevents neurite retraction in the specialized growth cone of developing neurons, and in fact promotes neurite outgrowth in the same fashion as microinjection of purified dominant negative RhoA T19N [ 39 ] . In these instances, neuronal N1E-115 cell outgrowth induced by inactivation of RhoA was mimicked by microinjection of Rac1- or Cdc42-GST fusion proteins, and could be abolished by coinjection of dominant negative Cdc42 T17Nor Rac1 T17N [ 39 ] . From these results, the authors concluded that inactivation of RhoA by C3 exoenzyme treatment resulted in the activation of Rac1 and Cdc42 GTPases, suggesting the mutually exclusive function of RhoA and Rac1/Cdc42.
The Rho family of GTPases is largely responsible for maintenance of cell shape in a variety of cell types, and this involves regulation of the actin cytoskeleton.
Western blot analyses of cytosol and particulate fractions obtained from the transfected 293 cells indicated that mycRab24(wt) was present in both fractions, consistent with previous results with Rab24 and other wild-type Rab GTPases [ 25 39 ] . In contrast, mycRab24(D123I) was found exclusively in the particulate fraction (Fig.
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