Words similar to gtpase
Example sentences for: gtpase
How can you use “gtpase” in a sentence? Here are some example sentences to help you improve your vocabulary:
Therefore, it appears that although the C-terminal domain of Rab24 is required to promote its incorporation into inclusion bodies, it does so only when expressed in the context of a Rab GTPase with a mutation in the N(T)KxD nucleotide binding motif.
This small member of the Ras GTPase superfamily has been implicated in fibroblast models of integrin dependent actin stress fiber formation, focal contact assembly [ 13 ] , and gene induction via the serum response element [ 14 ] . Studies of Rho function have been facilitated by the use of specific toxins such as Clostridium botulinum toxin C3 which catalyses the ADP-ribosylation and inactivation of Rho [ 15 16 17 ] . The function of this GTPase and related family members such as Rac and Cdc42 has been extensively studied in the fibroblast model.
One microliter of this mixture was applied to a polyethyleneimine cellulose thin layer chromatography plate and developed in 0.75 M KH 2PO 4. GDP produced was determined and the GTPase activity was expressed as mols GDP per mol FtsZ per min.
The main focus of the present study was to characterize the in vitro assembly and GTPase of the mutant proteins, but we also did a preliminary survey of their in vivo function by testing their ability to complement the temperature sensitive mutant ftsZ84.
The alanine substitution reduced the in vitro GTPase activity to 5% of wild type and appeared to eliminate the ability to form straight protofilaments, either alone or with 0.06 mg/ml DEAE dextran.
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