Words similar to glycosaminoglycan
- glycolytic
- glycopeptide
- glycopeptides
- glycophosphatidylinositol
- glycoprotein
- glycoprotein--the
- glycoproteins
- glycopyrrolate
- glycosaminglycans
- glycosaminoglycan
- glycosaminoglycan-degrading
- glycosaminoglycane
- glycosaminoglycans
- glycosidase
- glycosidases
- glycosyl-phophatidyniositol
- glycosylation
- glycotech
- glycyrrhetinic
Example sentences for: glycosaminoglycan
How can you use “glycosaminoglycan” in a sentence? Here are some example sentences to help you improve your vocabulary:
With regard to the repair phase, following IL-1-induced cartilage damage, relatively little is known, but partial to complete recovery appears possible [ 1 3 ] . In studies of repair, investigators focused on glycosaminoglycan (GAG) - an important and abundant cartilage macromolecule - and used histologic, biochemical, and/or radiolabel incorporation methods to measure GAG concentration ([GAG]) and/or GAG synthesis rates at selected time points.
High-density cartilage proteoglycan (aggrecan) was purified from human cartilage, by CsCl gradient centrifugation, and depleted of glycosaminoglycan side chains as described previously [ 21 ] . Female BALB/c mice (National Cancer Institute, Friedrich, MD, USA, or The Jackson Laboratory, Bar Harbor, ME, USA) and CD28-deficient mice (The Jackson Laboratory) were immunized intraperitoneally with cartilage proteoglycan (100 μg protein) in complete Freund's adjuvant on day 0, and boosted with proteoglycan in incomplete Freund's adjuvant on days 21 and 42.
PEDF, pigment epithelium-derived factor; GAG, glycosaminoglycan; HS, heparan sulfate; CM, media conditioned by retinoblastoma cells.
Aggrecan and versican are aggregating proteoglycans that are key constituents found in the extracellular matrix [ 41 ] . Both proteoglycans contain amino-terminal hyaluronic acid-binding regions, central core glycosaminoglycan attachment domains, and carboxyl-terminal domains containing EGF-like modules (one in aggrecan and two in versican), C-type lectin like modules and complement regulatory protein-like modules [ 49 50 ] . Fibulin-1 exhibits calcium-dependent binding to the carboxyl-terminal domain of aggrecan and versican [ 41 ] . The binding site of aggrecan to fibulin-1 maps to the type II EGF-like modules 8-9 and the carboxyl-terminal domain of fibulin-1 [ 41 ] . The binding site of versican to fibulin-1 maps to the type II EGF-like modules 2-8 of fibulin-1 [ 41 ] .
Regional analysis of glycosaminoglycan concentration recovery
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