Example sentences for: glycoproteins

How can you use “glycoproteins” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The effect of the phorbol ester 12-tetradecanoylphorbol-13 acetate (PMA) and exogenous cAMP on the levels of mRNA encoding the CD4 and CD8 glycoproteins was examined in human thymocytes.

  • In summary, the results presented here suggest that treatment of HIV-1 with CAP leads to conformational changes in the envelope glycoproteins, ultimately resulting, in the absence of target cell membranes, in the formation of gp41 six-helix bundles.

  • The secreted glycoproteins in the Wnt/Wingless (Wg) family serve diverse functions in developmental processes, ranging from cell fate specification and cell proliferation to cell migration and cell polarity [ 1 2 ] , and deregulation of the Wnt signaling pathway can lead to cancer [ 3 4 ] . In a simplified model of the canonical Wnt/β-catenin signaling pathway, the binding of Wnts to their receptors activates a downstream component, Dishevelled (Dsh).

  • Earlier studies describing the underlying molecular mechanisms involved in the HIV-1 inhibitory effect of the candidate microbicide CAP indicated that this compound remains bound to HIV-1, impairing virus infectivity by blockade of binding sites for cellular coreceptors CXCR4 and CCR5 [ 8 ] . Results reported here further extend these findings and show that: 1) there is synergism between sCD4 and CAP for inhibition of virus infectivity; 2) CAP binding to HIV-1 leads to conformational changes in viral envelope glycoproteins resulting in the expression of functionally inert six-helix bundle structures.

  • Wnt ligands are secreted glycoproteins that function in intracellular signaling pathways to regulate a variety of developmental processes including cell growth, cell differentiation, cell polarity, and apoptosis.


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