Words similar to glycoproteins
Example sentences for: glycoproteins
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Furthermore, interaction with micronized CAP elicits the formation of gp41 six-helix bundles and causes the stripping off of HIV-1 envelope glycoproteins (Fig.
Early during T-cell development in the thymic cortex, thymocytes bear both of the T cell surface glycoproteins CD4 and CD8 and express the α and β heterodimer of the TCR [ 4 ] . Compelling data have demonstrated that CD4 and CD8 molecules participate in the selection of MHC class I or class II restricted T cells in the thymus.
Earlier studies [ 8 ] , in which the binding of CAP treated and untreated virus with antibodies specific for distinct regions on the envelope glycoproteins gp120 and gp41 was studied, indicated that CAP had either no effect or caused decreased binding with antibodies against several peptides from gp120 but only against a single peptide, 557-586, from gp41 (see Discussion).
Scorpion venom when injected exerts a strong inflammatory response [ 11 ] . Many plant species used against stings contain compounds with antiinflammatory properties, flavonoids (rutin, hesperidin, quercetin), coumarins (bergapten), coumestans (wedelolactone), triterpenes, sterols and saponins [ 38 11 ] . The mechanism of action of the flavonoids is based on the inhibition of enzymatic steps in the arachidonic acid cascade [ 38 ] . Plant compounds that are immunostimulants at very low doses are some alkaloids, quinones, isobutylamides, phenolcarboxylic acid esters and terpenoids [ 39 ] . Other plant compounds with immunostimulatory effects are sesquiterpene lactones [ 40 ] . Many polysaccharides and glycoproteins enhance the unspecific immune system by activating the phagocytotic activity of granulocytes and macrophages, or by inducing cytokine production or influencing complement factors [ 39 ] .
Since CAP has a relatively high molecular weight (M w ~ 60,000; [ 2 ] ), its effect on HIV-1 virions would be expected to be confined to the virus surface, i.e. to the envelope glycoproteins gp120 and/or gp41.
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