Words similar to gag-binding

Example sentences for: gag-binding

How can you use “gag-binding” in a sentence? Here are some example sentences to help you improve your vocabulary:

GAG-binding proteins can be differentially sensitive to variations in GAG structure [ 27 ] . GAGs produced among different cell types have structural and compositional differences and structural changes in GAGs are known to occur in cells undergoing morphological differentiation and/or malignant transformations [ 28 29 30 31 ] . Thus, in the native retina, or other tissue, modulation of the PEDF-receptor interactions may depend on the expression of GAGs, which occur during development and pathological conditions.
It has been proposed that the GAG-binding property of PEDF provides the molecular basis for its association with extracellular matrices and may serve to localize PEDF activity in the retina and CNS [ 14 19 ] . However, the present results point to direct effects these polysaccharides might have on the biochemical interactions between PEDF and PEDF receptors on the surfaces of cells that respond to this neurotrophic factor.
Finally, the fact that the GAG and receptor binding regions are on opposite regions of the PEDF molecule, suggest the possibility of the existence of PEDF mutants or engineered variants that, having lost or decreased GAG-binding capabilities, still show high affinity for the PEDF receptor in a way not dependent upon GAGs content or composition.