Example sentences for: gaf

How can you use “gaf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A similar secondary structure pattern is also observed in several other ligand-binding domains such as the PAS, GAF, profilin and probably even the CACHE domains [ 10 ] . Sequence-structure threading using the 3DPSSM method detected the PAS domain (Photoactive yellow protein PDB: 1drm) with marginally significant scores (.5, 50-70% probability of correct fold prediction).

  • In such a scenario it could participate in allosteric regulation of the SGCs, similar to the GAF domains of the cyclic nucleotide phosphodiesterases [ 6 13 ] .

  • These include the PAS-like fold, which is the scaffold of the PAS [ 11 12 ] , GAF [ 13 ] , and probably the CACHE [ 14 ] superfamilies, and the ACT-like fold, which is seen in ACT, ferredoxin and related ligand-binding domains [ 4 15 ] . Identification of such conserved domains has, often, improved our understanding of the general structural and biochemical features that underlie protein-small molecule interactions.


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