Words similar to fibroblast
Example sentences for: fibroblast
How can you use “fibroblast” in a sentence? Here are some example sentences to help you improve your vocabulary:
From four original fibroblast samples, we generated clonally derived cell strains that expressed only the mutant MeCP2 or only the wild-type MECP2 allele, but not both.
Second, if the inter-clonal variation we detected by the quantitative RT-PCR study of 5 genes in 22 clones from two different Rett individuals were representative of a general feature of diploid fibroblast clones, it could have masked any consistent biologically meaningful expression changes.
Estrogen receptors have been identified in cultured fibroblasts of various origins and vascular smooth muscle cells [ 51 52 53 ] . Estrogens enhance proliferation of fibroblasts and inhibit vascular smooth muscle migration [ 54 55 ] . Binding of estrogens to fibroblasts also stimulates fibroblast interaction with epithelial cells with subsequent acceleration of maturation of epithelial cells [ 56 ] .
Previously we have described the interaction of the extracellular domain of proHB-EGF with the second extracellular domain of the tetraspanin protein, monkey CD9 [ 9 ] . Tissue culture experiments using DT-sensitive transfected mouse fibroblast cell lines expressing on the cell surface both the monkey DT receptor and chimeric mouse-monkey CD9 antigen showed that the second extracellular domain of monkey CD9 antigen is able to act as a coreceptor for DT and is also responsible for the increased DT-sensitivity and affinity for DT in these cell lines [ 9 ] . These observations suggested that the CD9 antigen and proHB-EGF likely interact physically on the cell surface.
Both these fibroblast lines, although derived from morphologically female genitalia in phenotypically female 46,XY individuals mosaic for AR-inactivating mutations, expressed wild-type AR in the cultured cells.