Words similar to fibrosarcoma
Example sentences for: fibrosarcoma
How can you use “fibrosarcoma” in a sentence? Here are some example sentences to help you improve your vocabulary:
Media from a HT-1080 fibrosarcoma cell line was used as a positive control for MMP-2 and MMP-9 activity.
Fibrosarcoma PAI-1, wtPAI-1 or its mutants were denatured with 6 M guanidine-hydrochloride (Gdn-HCl) (45 min at 37°C), followed by dialysis (4-16 hours at 4°C) against 50 mM sodium acetate, pH 5.6, containing 0.5 M NaCl and 0.01% Tween-20.
Volpert and colleagues demonstrated this phenomenon using tumors formed by the human fibrosarcoma line HT1080 in nude mice, and obtained data indicating that it was caused by secretion of TSP-1 by the primary tumor [ 27 ] . Some of the properties attributed to TSP-1 are conflicting, however; TSP-1 can be both adhesive and anti-adhesive in vitro , can stimulate or inhibit angiogenesis, and can inhibit or enhance proteolytic enzyme activity.
The high specific inhibitory activity of wt-PAI-1 could be due to the fact that it was secreted from insect High-5 cells cultured at 27°C, while the fibrosarcoma preparation of PAI-1 was obtained from the medium of fibrosarcoma cells cultured at 37°C [ 20 ] . Exposure to the higher temperature could accelerate the conversion of the inhibitor into its latent form.
The second-order rate constants for the interaction of the fibrosarcoma PAI-1, wtPAI-1 or the indicated mutants with single-chain tPA or uPA were determined in a single-step assay as previously described.