Words similar to fibulin-
Example sentences for: fibulin-
How can you use “fibulin-” in a sentence? Here are some example sentences to help you improve your vocabulary:
Fibulin-1 may serve to anchor the mHB-EGF to its fibers as it migrates through the extracellular matrix.
As described above, the calcium-binding type II EGF-like modules of fibulin-1 are used in various extracellular matrix interactions.
Fibronectin contains three types of homology sequences, I-III; type I sequences bind heparin, Staphylococcus aureus, fibrin, and cell surfaces, type II sequences bind collagen and gelatin, and type III sequences bind DNA, cell surfaces, heparin, and fibulin-1 [ 40 43 ] . Fibulin-1 interacts with fibronectin through a heparin-binding region in type III 13 repeat; the binding of fibulin-1 to this site is independent of the binding of heparin as addition of exogenous heparin does not inhibit fibulin-1 binding to fibronectin [ 40 ] . The fibronectin-binding site in fibulin-1 is located in EGF-like modules 5 and 6 [ 44 ] ; the binding of fibulin-1 to fibronectin is a heterotypic interaction in which an EGF-like module binds to a non EGF-like domain (the type III 13 fibronectin repeat) [ 40 ] .
Fibulin-1 is incorporated into fibronectin-containing matrix fibers [ 44 51 ] . Although a distinct function for fibulin-1 has not yet been described, it is conceivable that fibulin-1 is important for cell adhesion and migration along protein fibers within the extracellular matrix.
The results presented in this paper now suggest that there is potential in carrying out experiments to further delineate the molecular interactions between proHB-EGF and LTBP-3 and between proHB-EGF and fibulin-1C.
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