Words similar to fibulin-
Example sentences for: fibulin-
How can you use “fibulin-” in a sentence? Here are some example sentences to help you improve your vocabulary:
Fibulin-1 is incorporated into fibronectin-containing matrix fibers [ 44 51 ] . Although a distinct function for fibulin-1 has not yet been described, it is conceivable that fibulin-1 is important for cell adhesion and migration along protein fibers within the extracellular matrix.
Fibulin-1 may serve to anchor the mHB-EGF to its fibers as it migrates through the extracellular matrix.
The interaction of fibulin-1C may map to the heparin-binding region of the extracellular domain of proHB-EGF or it may map to the EGF-like module of proHB-EGF or it may map to both of these regions within proHB-EGF.
Fibronectin contains three types of homology sequences, I-III; type I sequences bind heparin, Staphylococcus aureus, fibrin, and cell surfaces, type II sequences bind collagen and gelatin, and type III sequences bind DNA, cell surfaces, heparin, and fibulin-1 [ 40 43 ] . Fibulin-1 interacts with fibronectin through a heparin-binding region in type III 13 repeat; the binding of fibulin-1 to this site is independent of the binding of heparin as addition of exogenous heparin does not inhibit fibulin-1 binding to fibronectin [ 40 ] . The fibronectin-binding site in fibulin-1 is located in EGF-like modules 5 and 6 [ 44 ] ; the binding of fibulin-1 to fibronectin is a heterotypic interaction in which an EGF-like module binds to a non EGF-like domain (the type III 13 fibronectin repeat) [ 40 ] .
As described above, the calcium-binding type II EGF-like modules of fibulin-1 are used in various extracellular matrix interactions.
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