Example sentences for: fibrotic

How can you use “fibrotic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In addition, patients with a favorable outcome had larger PPD skin test reactions, higher absolute CD4+ cell counts, lower serum β 2 microglobulin levels, and were more likely to have fibrotic changes on their initial chest x-ray, than subjects with an unfavorable outcome.

  • Bein et al also found that patients with more severe lung disease (Murrary Lung injury score more than 2.5) did not respond to rotational therapy, whereas those with less severe disease (less than 2.5) had significant changes in P a O 2 /FIO 2 . This can be explained by the changes in ARDS with time, as the lung evolves from a wet, heavy, atelectatic lung to a brittle fibrotic lung [ 12].

  • Vancheri and collaborators [ 20 ] found that TNF-α-stimulated fibrotic lung fibroblasts had decreased COX-2 expression and PGE 2 production, but they further showed that these findings were a result of decreased expression of TNF-α receptors.

  • [ 21 ] reported that fibrotic lung fibroblasts had decreased COX-2 expression and PGE 2 production in response to TGFβ stimulation.

  • Despite significant progress towards understanding the pathogenesis of SSc and other fibrotic diseases, effective treatment is still lacking.


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