Words similar to fibroadenomas

Example sentences for: fibroadenomas

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These observations differ from a recent report that one of the other two Pten +/- lines develops fibroadenomas and adenocarcinomas in the mammary tissue after 7 months of age [ 26].
This finding and the observation that fibroadenomas (non-malignant tumors) can express BP1 strongly suggest that its activation might be associated with loss of growth regulation, which is consistent with our molecular data.
While benign mammary lesions, usually fibroadenomas, are found in female mice after 7 months of age, few animals develop ductal carcinomas [KP and RP, unpublished; 26], which account for over 85% of human breast cancers.
We have therefore begun to examine ductal carcinoma in situ (DCIS), which are preinvasive malignant lesions derived from epithelial cells, and fibroadenomas, which are non-malignant tumors composed of epithelial and stromal cells [ 32 33 ] . So far we have analyzed one DCIS, which was BP1-positive, and two fibroadenomas, both of which were BP1-positive, compared with no expression in the matched normal tissue for each fibroadenoma (data not shown).
Sixty-eight frozen human breast tissue specimens were evaluated by LCM, qPCR and IHC, including 31 primary tumors of infiltrating ductal carcinomas (22 primary tumors with metastasis and nine primary tumors without known metastasis), 22 matched nodal metastases, 10 fibroadenomas and five normal breast tissues (obtained from reduction mammoplasty).