Words similar to endotoxin-induced

Example sentences for: endotoxin-induced

How can you use “endotoxin-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:

Moreover, treatment of the macrophages with SN50, a cell-permeable peptide that specifically prevents activation of NF-κB by inhibiting its nuclear translocation [34], nearly abolished endotoxin-induced activation of resistin expression (Figure 4D).
Recent studies have suggested that phagocytic leukocytes including macrophages and neutrophils contribute to the pathophysiology of endotoxin-induced lung injury [ 22 ] . Whereas macrophages are normally present in the tissue, the majority of neutrophils responding to endotoxin must emigrate into the lung from the blood.
The transcription factors NF-κB and CREB have been reported to activate COX-2 in LPS-stimulated monocytes and macrophages in vitro [ 48 49 ] . Moreover, endotoxin-induced increases in neutrophil TNF-α, as well as interleukin-1β and MIP-2 in vivo appear to be mediated by NF-κB and CREB [ 21 ] . We found that activated NF-κB and CREB were present in the nucleus of adherent vascular lung neutrophils from endotoxemic, but not control rats, suggesting that these transcription factors play a role in increased responsiveness of the cells.
Further studies are needed to determine the precise role of these signaling molecules in endotoxin-induced inflammatory responses in the lung.
Indeed, treatment of the macrophages with the proteasome inhibitor MG132, which prevents NF-κB activation [33], abrogated endotoxin-induced activation of resistin expression (data not shown).