Words similar to endotoxin-induced

Example sentences for: endotoxin-induced

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Moreover, treatment of the macrophages with SN50, a cell-permeable peptide that specifically prevents activation of NF-κB by inhibiting its nuclear translocation [34], nearly abolished endotoxin-induced activation of resistin expression (Figure 4D).
Recent studies have suggested that phagocytic leukocytes including macrophages and neutrophils contribute to the pathophysiology of endotoxin-induced lung injury [ 22 ] . Whereas macrophages are normally present in the tissue, the majority of neutrophils responding to endotoxin must emigrate into the lung from the blood.
Further studies are needed to determine the precise role of these signaling molecules in endotoxin-induced inflammatory responses in the lung.
Remarkably, aspirin dramatically decreased endotoxin-induced resistin expression in a dose-dependent manner (Figure 4C).
The transcription factors NF-κB and CREB have been reported to activate COX-2 in LPS-stimulated monocytes and macrophages in vitro [ 48 49 ] . Moreover, endotoxin-induced increases in neutrophil TNF-α, as well as interleukin-1β and MIP-2 in vivo appear to be mediated by NF-κB and CREB [ 21 ] . We found that activated NF-κB and CREB were present in the nucleus of adherent vascular lung neutrophils from endotoxemic, but not control rats, suggesting that these transcription factors play a role in increased responsiveness of the cells.