Words similar to endotoxemia
Example sentences for: endotoxemia
How can you use “endotoxemia” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is normally cleared from the blood by macrophages of the reticuloendothelial system predominantly localized in the liver [ 1 ] . Acute endotoxemia, characterized by excessive levels of endotoxin in the blood, can lead to endothelial injury, hypotension, multi-organ failure and death [ 1 ] . Endotoxin-induced tissue injury is associated with an inflammatory response and an accumulation of phagocytes at sites of damage.
We next examined biochemical signaling pathways known to regulate cell survival and activation to determine if their expression was altered in adherent vascular lung neutrophils during acute endotoxemia.
Previously, MIF was described in the epithelia of several organs of the rat [ 6 ] . The present findings provide anatomical evidence of MIF protein in the bladder and prostate epithelia of the rat and confirm our earlier findings demonstrating MIF expression in the bladder by immunohistochemistry, Western blotting analysis and RT-PCR [ 10 11 ] . In other organs, the MIF stored in the epithelia was released upon endotoxemia [ 7 ] . As such, MIF may form part of the innate immune response of different organs to bacterial infection.
Acute endotoxemia caused a marked induction of Mcl-1 in freshly isolated adherent vascular lung neutrophils, which peaked between 2 and 12 hours and remained elevated for at least 48 hours.
The increase in resistin protein levels correlated with increased resistin gene expression in peripheral blood mononuclear cells following systemic endotoxemia (Figure 5B).
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