Example sentences for: endotoxemia

How can you use “endotoxemia” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Induction of acute endotoxemia caused a rapid (within 0.5 hours) and persistent increase in expression of both proteins.

  • These findings suggest a potential mechanism mediating decreased apoptosis and increased functional activation of adherent vascular neutrophils in the lung during acute endotoxemia.

  • Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that may play a role in several disease states, including arthritis, sepsis, Crohn's disease, allograft rejection, asthma and prostate cancer [ 1 2 3 ] . Although MIF was initially described as released from activated T-cells [ 4 5 ] , subsequent investigations have localized MIF in a variety of other cells and tissues (for a recent review [ 1 ] ). For example, pre-formed MIF stores can be found in the epithelia of several organs and may be released in response to endotoxemia [ 6 ] . The role of MIF in the central nervous system remains to be determined, yet neurons in the brain synthesize and rapidly release MIF while glial cells appear to store MIF [ 7 8 ] , and the anterior pituitary gland contains MIF that may be released during endotoxemia [ 9 ] .

  • Remarkably, resistin levels rose dramatically because of endotoxemia, peaking 8–16 h after LPS administration (Figure 5A).

  • Acute endotoxemia also rapidly induced NF-κB and CREB, as well as total p38 and p44/42 MAP kinases.


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