Words similar to endotoxemia
Example sentences for: endotoxemia
How can you use “endotoxemia” in a sentence? Here are some example sentences to help you improve your vocabulary:
Acute endotoxemia caused a marked induction of Mcl-1 in freshly isolated adherent vascular lung neutrophils, which peaked between 2 and 12 hours and remained elevated for at least 48 hours.
The effects of acute endotoxemia on expression of PI3K and its downstream target PKB-α were also investigated.
Similar transient increases in neutrophil chemotaxis and pulmonary TNF-α production have been described previously during experimentally induced endotoxemia [ 32 33 ] . These findings are consistent with the idea that chemotaxis and TNF-α production are important in early inflammatory responses of neutrophils [ 34 ] . In contrast, protein levels for COX-2 remained elevated for 48 hours after endotoxin administration.
Experimental endotoxemia in healthy volunteers, based on the well-established gram-negative bacterial inflammatory response in humans [38,39,40], induces a dramatic elevation of circulating resistin levels.
It is normally cleared from the blood by macrophages of the reticuloendothelial system predominantly localized in the liver [ 1 ] . Acute endotoxemia, characterized by excessive levels of endotoxin in the blood, can lead to endothelial injury, hypotension, multi-organ failure and death [ 1 ] . Endotoxin-induced tissue injury is associated with an inflammatory response and an accumulation of phagocytes at sites of damage.