Words similar to endotoxemia
Example sentences for: endotoxemia
How can you use “endotoxemia” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the present study, we characterized the effects of acute endotoxemia on the response of a unique population of neutrophils, which we have previously demonstrated are tightly adhered to the lung vasculature [ 9 ] . Because of their location within the tissue, these cells are likely to be more relevant than circulating neutrophils, or neutrophils recovered by bronchoalveolar lavage (BAL), to the pathophysiology of endotoxin induced lung injury.
To determine whether acute endotoxemia activated adherent vascular lung neutrophils for increased functional responsiveness, we initially analyzed their chemotactic activity towards bacterially-derived fMLP.
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that may play a role in several disease states, including arthritis, sepsis, Crohn's disease, allograft rejection, asthma and prostate cancer [ 1 2 3 ] . Although MIF was initially described as released from activated T-cells [ 4 5 ] , subsequent investigations have localized MIF in a variety of other cells and tissues (for a recent review [ 1 ] ). For example, pre-formed MIF stores can be found in the epithelia of several organs and may be released in response to endotoxemia [ 6 ] . The role of MIF in the central nervous system remains to be determined, yet neurons in the brain synthesize and rapidly release MIF while glial cells appear to store MIF [ 7 8 ] , and the anterior pituitary gland contains MIF that may be released during endotoxemia [ 9 ] .
Induction of acute endotoxemia caused a rapid (within 0.5 hours) and persistent increase in expression of both proteins.
Animals were housed in microisolator cages and were maintained on sterile food and pyrogen-free water ad libitum . Acute endotoxemia was induced by i.v.
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