Words similar to endothelin

Example sentences for: endothelin

How can you use “endothelin” in a sentence? Here are some example sentences to help you improve your vocabulary:

In another version of this study published previously, it was seen that ibuprofen reduced the endothelin production induced by endotoxin administration [ 31 ] .
Several vasoactive G-protein coupled agonists, including angiotensin II and endothelin, have also been shown to activate the ERK pathway in vascular smooth muscle cells [ 6 21 ] . These same hormones also activate the JNK and p38 pathways.
The activation of p38 and JNK pathways by angiotensin II and endothelin occurs at higher concentrations of agonist and requires a longer incubation with the stimulus [ 18 19 25 ] . There are data which also suggest that different signal transduction pathways are utilized for the different pathways [ 25 26 27 ] . This differential activation of MAPK pathways is most likely due to the role that each plays in the cell.
Altered vascular function in older individuals is evidenced as impaired endothelial function [ 8 9 10 ] , an altered ratio of endothelin receptors [ 11 ] , and/or altered reactivity of the smooth muscle to sympathetic activity [ 7 12 ] . Reduced endothelial function is related to impaired formation and decreased activation of nitric oxide [ 13 14 ] and is particularly prominent in older subjects with evidence of cardiovascular disease [ 15 ] , diabetes [ 16 ] , or obesity [ 17 ] . Interestingly, aging does not appear to effect endothelium independent vasodilation [ 10 14 ] .