Words similar to endostatin
Example sentences for: endostatin
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In short, HeLa cells were incubated for 2 days with the Ad Adapt human endostatin and the medium was collected.
In addition, recent work has shown that cells interact with endostatin through two classes of receptors; integrins and glypicans (cell surface HSPGs) [ 48 49 ] . This parallels our findings in this present report, that cells interact with III1-C through integrins and cell surface HSPGs.
It is assumed that no significant effect is expected from a therapeutic transgene (e.g thymidin kinase, mhATF-BPTI or endostatin) if the percentage of transduced tumour tissue is below 5%.
Other investigators described differences of the same order of magnitude between mouse strains in expression of transgenes encoding α1-antitrypsin [ 1 ] , interleukin-12 [ 2 ] , and human endostatin [ 3 ] . These differences in transgene expression between inbred species may have clinical implications, as differences between inbred strains are considered to reflect differences between individuals of an outbred species.
The ED50 of endostatin (1000 ng / ml) was in the range of published data [ 25 ] . Further, the angiostatic and antitumoral activities of the human endostatin has been demonstrated in different rat models [ 26 27 28 ] .