Example sentences for: endonuclease

How can you use “endonuclease” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • They concluded that the long term persistence of the intron depends on a cycle that begins with invasion of the empty target site by an intron with the help of a homing endonuclease encoded by an open reading frame within the intron.

  • The salient features of such a vector are shown in Fig 2. A unique SalI restriction endonuclease site allows the introduction of coding sequences into this vector.

  • The endonuclease activity of DNase 1 is reduced many fold by integrating this loop from E. coli exonuclease III, but the mutant cleaves at abasic sites in DNA with low efficiency [ 29 ] . Thus additional residues in the APEs control specificity while still allowing a reasonable rate of phosphorolytic cleavage.

  • For ORF2, key residues for endonuclease activity include the residues at positions 12(N), 43(E), 115(Y), 145(D), 147(N), 192(T), 205(D), and 228-230(SDH) [ 12].

  • The translation for each full-length L1 sequence was analyzed for the presence of nonsense mutations, and for missense mutations that inhibit retrotransposition activity by destroying the catalytic sites of the endonuclease or reverse transcriptase or any other critical residues on which retrotransposition depends (see Materials and methods for a complete list) [ 12, 14, 46].


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