Words similar to endonuclease

Example sentences for: endonuclease

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Multiple sequence alignments of diverse intein sequences identified eight motifs composed of moderately conserved residues [ 18 28 ] . The A-ATPase A subunit of the Thermoplasma and Pyrococcus intein multiple sequence alignment (with manual modification) is shown in figure 1. The T. acidophilum intein (173 amino acids long) is among the shortest inteins known, and the alignment with other inteins reveals the absence of sequences homologous to the typical endonuclease motifs.
During this process, called homing, the gene encoding the intein-free homolog is cleaved by the endonuclease at or close to the intein integration site.
The endonuclease activity of DNase 1 is reduced many fold by integrating this loop from E. coli exonuclease III, but the mutant cleaves at abasic sites in DNA with low efficiency [ 29 ] . Thus additional residues in the APEs control specificity while still allowing a reasonable rate of phosphorolytic cleavage.
At least the former, and perhaps even the latter, appear to belong to a large class of nucleic-acid-binding domains that includes the APSES, LAGLIDADG endonuclease and TEN domains.
First, Dlakic [ 12 ] and Hofmann et al [ 13 ] showed that the yCCR4 C-terminus contains a fold related to the Mg 2+-dependent endonuclease core, suggesting that it may function as a nuclease.