Example sentences for: endonucleases

How can you use “endonucleases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have chosen to illustrate this approach using the multifunctional family of DNA repair proteins, the apurinic/apyrimidinic endonucleases (APEs), which have a clearly defined bacterial ancestor, E. coli exonuclease III (ExoIII), and are distantly related to several enzymes with varying substrate specificity.

  • This alignment could be extended to the enzymatic core of three characteristic Mg 2+-dependent endonucleases: the bovine DNAseI [ 29 ] and two apurinic/apyrimidinic (AP) DNA-repair endonucleases, i.e. the E. coli Exonuclease III [ 30 ] and the human HAP1 protein [ 31 ] . These nucleases share the same catalytic residues and form a similar four-layered α/β-sandwich motif.

  • Both methods allow similarly large numbers of mutational variants to be simultaneously compared and competed, and both methods can potentially be adapted to a range of molecular biology enzymes that act on their own templates, such as restriction endonucleases or DNA ligases.

  • Like the KilA-N domains that are mainly associated with DNA viruses, the LAGLIDADG endonucleases are predominantly encoded by mobile genetic elements [ 31].

  • We noticed, however, that, although the TEN domain is related to the LAGLIDADG endonucleases, the active-site residues are not preserved in the former, and the TEN domain probably functions as a RNA-binding domain rather than a nuclease.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast