Words similar to endonucleases
Example sentences for: endonucleases
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Inteins without this domain perform autocatalytic splicing [ 15 16 ] . Homing endonucleases and the process of homing have been more intensively studied in self splicing introns [ 17 ] , and the process is assumed to be similar for inteins.
Dlakic [ 12 ] and Hofmann et al [ 13 ] recently reported that the xe.nocturnin and yCCR4 proteins contain a domain with similarities with the enzymatic core of Mg 2+-dependent endonucleases.
Even small proteins may contain several individual domains that link them to different superfamilies [ 2 ] . While many endonucleases share a common active site that is highly conserved across many subfamilies, identifying residues that control substrate specificity requires sophisticated analysis that combines both sequence conservation and structural data [ 3 4 5 ] .
Like the KilA-N domains that are mainly associated with DNA viruses, the LAGLIDADG endonucleases are predominantly encoded by mobile genetic elements [ 31].
We noticed, however, that, although the TEN domain is related to the LAGLIDADG endonucleases, the active-site residues are not preserved in the former, and the TEN domain probably functions as a RNA-binding domain rather than a nuclease.