Example sentences for: endonucleases

How can you use “endonucleases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Detailed procedures for isolation of total RNA, enrichment of poly (A)+ RNA by oligo-dT cellulose chromatography and electrophoresis and Northern blotting of RNA have been described previously [ 13 ] . The cDNA probes of mouse RAR α and RAR γ [ 21 22 ] were isolated by agarose electrophoresis after appropriate endonucleases digestion and were radio-labeled with 32P-dCTP, using random priming kit (Boehringer-Mannheim, Indianapolis, IN).

  • Our search of the genomes of these Archaea did not identify any endonucleases that might function in homing.

  • We have chosen to illustrate this approach using the multifunctional family of DNA repair proteins, the apurinic/apyrimidinic endonucleases (APEs), which have a clearly defined bacterial ancestor, E. coli exonuclease III (ExoIII), and are distantly related to several enzymes with varying substrate specificity.

  • Structural comparisons using the DALI program [ 20], indicated that the core fold shared by the KilA-N and APSES domains is more distantly related to the LAGLIDADG site-specific DNA endonucleases and the amino-terminal domain of the tRNA splicing endonucleases (TEN domain) (Figure 1b) [ 21].

  • Dlakic [ 12 ] and Hofmann et al [ 13 ] recently reported that the xe.nocturnin and yCCR4 proteins contain a domain with similarities with the enzymatic core of Mg 2+-dependent endonucleases.


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