Words similar to endosomes
Example sentences for: endosomes
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No actin structures were seen in association with these bacteria, implying that they were indeed deficient in virulence gene expression and failed to escape from the endosomes (Figure 1d).
Co-localization experiments indicate that all of the OxyBURST Green H 2 HFF BSA is distributed in lysosomes but not endosomes after this labeling procedure (see below).
Furthermore, cells were incubated with the OxyBURST Green H 2 HFF at 37°C for 10 min so that the reduced dye is transported primarily into endosomes rather than lysosomes.
Mycobacteria enter macrophages primarily by conventional receptor-mediated phagocytic pathways [ 3 ] . Following phagocytosis, phagosomes containing viable tubercle bacilli fail to acidify, apparently because of failure to insert a proton-ATPase pump into the phagosomal membrane [ 4 5 6 ] . This leads to altered vacuolar maturation such that phagosome-lysosome fusion is blocked and the mycobacteria-containing vacuoles end up with an internal pH of about 6 and markers of phagosomes and early and late endosomes [ 7 8 9 10 11 ] . The mycobacterial genes responsible for these processes are largely unknown.
PLD1 is an extracellular signal-activated phospholipase; its activity rises when receptors for certain hormones, growth factors, neurotransmitters, cytokines, and other mediators are activated, and upon treatment of cells with phorbol esters (reviewed in [ 7 8 ] ). Studies using recombinant PLD1 tagged with green fluorescent protein or Flu-epitopes indicate that it is localized in the endoplasmic reticulum, Golgi apparatus, late endosomes, and plasma membrane ( [ 6 ] , reviewed in [ 7 ] ). In vitro, basal PLD1 activity is usually low and can be stimulated by a variety of factors, including phosphatidylinositol 4, 5-bisphosphate (PIP 2 ), protein kinase C (PKC), and several small GTPases, e.g.
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