Words similar to dpbbs

Example sentences for: dpbbs

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The minimal RNA polymerase seems to be represented by the predicted catalytic core of Cgl1702, which appears to consist entirely of the β-type and β'-type DPBBs, in this case juxtaposed in the same polypeptide.
However, the DPBBs from the two DDRP subunits are spatially juxtaposed in the DDRP crystal, with the catalytic cleft located between them.
Thus, these specific active residues apparently emerged after the divergence of the β and β' subunit DPBBs, whereas the ancestral DPBB homodimer probably did not have catalytic activity and merely bound a ribozyme that originally catalyzed the RNA polymerization.
This arrangement suggests that the primordial RNA polymerase was a head to tail homodimer of a DPBB domain; a duplication of this primordial DPBB domain probably gave rise to the two DPBBs of modern DDRPs.
This observation, taken together with the spatial proximity of the two DPBBs in the catalytic cleft of the DDRP (Fig.