Words similar to dpbbs

Example sentences for: dpbbs

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Thus, these specific active residues apparently emerged after the divergence of the β and β' subunit DPBBs, whereas the ancestral DPBB homodimer probably did not have catalytic activity and merely bound a ribozyme that originally catalyzed the RNA polymerization.
Of these, the small residues preceding strands 3 and 6 contribute a positive φ angle, which results in turning of the C-α backbone to stabilize the β-barrel [ 62 ] . These shared features notwithstanding, the ancient DPBBs have no conserved residues in their catalytic or substrate-binding sites.
The arrangement of the two DPBBs in the β and β' subunits suggests that, in the primordial ancestor of the DDRPs, the two DPBBs formed a "head-to-tail" homodimer that bound RNA at the domain interface.
However, the DPBBs from the two DDRP subunits are spatially juxtaposed in the DDRP crystal, with the catalytic cleft located between them.
The psi-loops between strands 1 and 2 and between strands 4 and 5 often harbor the active site or substrate-interaction residues of the respective DPBBs.