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Example sentences for: dpbbs

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This arrangement suggests that the primordial RNA polymerase was a head to tail homodimer of a DPBB domain; a duplication of this primordial DPBB domain probably gave rise to the two DPBBs of modern DDRPs.
Of these, the small residues preceding strands 3 and 6 contribute a positive φ angle, which results in turning of the C-α backbone to stabilize the β-barrel [ 62 ] . These shared features notwithstanding, the ancient DPBBs have no conserved residues in their catalytic or substrate-binding sites.
In contrast, the DPBBs detected in DDRP subunits are universally present in all modern life forms and hence are traceable to LUCA.
Furthermore, the SBHM also contributes to the stabilization of the catalytic site by forming an interface between the two DPBBs (Fig.
This observation, taken together with the spatial proximity of the two DPBBs in the catalytic cleft of the DDRP (Fig.