Words similar to dpbb

Example sentences for: dpbb

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An alternative scenario holds that the RDRPs are ancient enzymes that diverged from the evolutionary precursor of DDRP at a very early, pre-LUCA stage of evolution, albeit after the duplication that led to the differentiation of the β and β' versions of the DPBB domain.
Importantly, approximately 10 conserved residues that are detected in the structure-based alignments of the DPBB domains are also conserved in the RDRPs (Fig.
Based on the crystal structure, it has been proposed that the region containing the Zn ribbon may interact with the promoter during transcription initiation in bacteria [ 23 ] . Hence, it is plausible that a nucleic-acid-binding Zn-ribbon had been recruited to the ancestral polymerase core, which consisted of the DPBB domains, and contributed to non-specific interactions with the template.
This latter form was recruited into the RNA polymerase catalytic core where it provided additional surfaces for the interaction between the DPBB domains and formed part of the interface between the catalytic domains.
An alternative, perhaps more likely explanation is that, while the core catalytic domains of the two polymerases evolved from the same ancestral DPBB, they subsequently accreted distinct sets of peripheral modules around this core.