Words similar to dpbb

Example sentences for: dpbb

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An alternative scenario holds that the RDRPs are ancient enzymes that diverged from the evolutionary precursor of DDRP at a very early, pre-LUCA stage of evolution, albeit after the duplication that led to the differentiation of the β and β' versions of the DPBB domain.
Additionally, two AT-hook like modules, which probably had an accessory DNA-binding function, were also inserted into a conserved α-helix directly N-terminal of the DPBB domain in the β' subunit.
1) and might functionally correspond to the conserved lysines of the β-type DPBB.
This domain adopts the DPBB fold, in which the signature DbDGD motif, shared by RDRP and DDRP, is ensconced in the insert between the ultimate and penultimate β-strands.
This version of the DPBB domain lacks the metal-coordinating motif but contributes two lysine residues, which are critical for substrate interactions in the catalytic cleft.