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Example sentences for: dpbb

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Mirroring the insertion of the ASCR domain in the β' subunit, a distinct α + β globular domain, N-terminal to the DPBB domain (region 578-632 of 1K83, Chain B), is inserted in the β subunits of all archaeal and eukaryotic DDRPs (Fig.
4) are compatible with the hypothesis that the two DPBB domains of DDRP shared a common ancestor to the exclusion of the other ancient, FDHC-like DPBB.
The above analysis shows that LUCA probably encoded three distinct DPBB domains.
This domain adopts the DPBB fold, in which the signature DbDGD motif, shared by RDRP and DDRP, is ensconced in the insert between the ultimate and penultimate β-strands.
The region of structural similarity shared by the catalytic domain of the β' subunit of the DDRPs and the above proteins corresponds to a distinct globular fold known as the double-psi beta-barrel (DPBB) [ 62 63 64 ] . The SCOP database included the RNA polymerase subunits in the multidomain protein class but mentions the presence of a DPBB domain in each of the β and β' subunits ( [ 65 ] ; see below).