Example sentences for: dnmt

How can you use “dnmt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • ARS consensus sequence has been found near the vicinity of c-myc, lamin beta 2 and Dnmt1 replication origin [ 26 ] . Therefore, Identification and characterization of this protein from insect cells and finding its human counterpart will greatly help in elucidating its possible function in DNA replication.

  • In S. cerevisiae , ARS elements have been implicated to be important both for ORC binding and origin function [ 6 ] . We looked for the availability of such sequences in known human origins of replication like c-myc, lamin beta 2 and Dnmt1.

  • A unique feature of GCTs is their origin from germ cells at a stage in development where they undergo epigenetic reprogramming [ 6 13 ] . The absence of this epigenetic modification in SGCTs is consistent with their GC-like nature as previously noted [ 6 14 ] . On the other hand, the extensive promoter hypermethylation seen in NSGCTs suggests a mechanistic role in their potential for embryonal and extra-embryonal lineage differentiation [ 6 14 ] . Establishment of DNA methylation in the mammalian genome is controlled by at least three DNA methyltransferases (DNMTs), DNMT1 , DNMT3a and DNMT3b [ 15 ] . The role of these DNMTs in differential de novo methylation in SGCT vs.


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