Words similar to dnp

Example sentences for: dnp

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As with most chronic degenerative kidney diseases, the gradual decline of renal function at later stages of DNP is invariably associated with tubular epithelial degeneration (TED), also called tubular atrophy, and interstitial fibrosis (IF), hallmarks of degeneration to end-stage renal failure [3].
Although TED and IF are the strongest predictors for progression of DNP [31], mechanisms that underlie TED in DNP remain poorly understood.
These findings indicate that in humans with DNP, diabetes-induced upregulation of CD36 expression in proximal tubules was associated with moderate to advanced stages of TED and IF.
In contrast, TED and IF were associated with moderate to advanced mesangial expansion and glomerulosclerosis on kidney sections of human DNP (Figure 2B).
These findings are consistent with a recent uncontrolled case series of five patients with DNP [34], and with previous reports demonstrating tubular apoptosis in kidneys of STZ-treated diabetic rats [35,36].