Example sentences for: dnp

How can you use “dnp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Based on our in vitro and in vivo findings we propose a two-step metabolic hit model for TED in DNP.

  • Specifically, we show that glucose stimulates CD36 cell surface expression in proximal tubular epithelial cells (PTECs), and increased CD36 renders PTECs susceptible to both AGE- and PA-induced PTEC apoptosis by mediating sequential activation of src kinase, proapoptotic p38 MAPK, and caspase 3. Based on these findings, we propose a new two-step metabolic hit model for TED in the progression of DNP.

  • These findings are consistent with a recent uncontrolled case series of five patients with DNP [34], and with previous reports demonstrating tubular apoptosis in kidneys of STZ-treated diabetic rats [35,36].

  • Although TED and IF are the strongest predictors for progression of DNP [31], mechanisms that underlie TED in DNP remain poorly understood.

  • These findings indicate that in humans with DNP, diabetes-induced upregulation of CD36 expression in proximal tubules was associated with moderate to advanced stages of TED and IF.


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