Words similar to dnase

Example sentences for: dnase

How can you use “dnase” in a sentence? Here are some example sentences to help you improve your vocabulary:

We then demonstrated that the shared molegos served a similar role in substrate binding by comparing the DNA binding profile of huAPE1 with that for the less specific enzyme DNase 1. The molegos present in both enzymes interact with target DNA in a similar fashion, while residues in molegos distinctive for APE1 control specificity by binding primarily to the bases around the apurinic site.
A specific complex that formed a Dnase I footprint (-306 to -265) in the cAMP-responsive region of the RIIβ promoter in granulosa cells [ 18 ] , covers a consensus E-box (CACGTG) known to bind helix-loop-helix (bHLH) transcription factors.
The endonuclease activity of DNase 1 is reduced many fold by integrating this loop from E. coli exonuclease III, but the mutant cleaves at abasic sites in DNA with low efficiency [ 29 ] . Thus additional residues in the APEs control specificity while still allowing a reasonable rate of phosphorolytic cleavage.
DNase I digestion reaction and footprinting gel followed published techniques [ 16 ] .
The extensive contacts that APE1 makes to these positions are mediated by molegos it does not share with DNase 1. Molegos 6, 7a and 10 all have residues within hydrogen bonding distance of the three basepairs 3' of the AP-site.