Example sentences for: disrupting

How can you use “disrupting” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cell lysates for small scale immunoprecipitations were prepared by disrupting cells in immunoprecipitation buffer (20 mM Tris/HC1, pH7.

  • For example, exon-skipping mutations in the central region of the gene, exons 24-32, cause severe phenotypes or neonatal presentations [ 8 ] . But there are exceptions, only four of the many other mutations in this region cause severe phenotypes, while one mutation predicted to lead to skipping of exon 24 was found in a patient with classic MFS [ 5 ] . In contrast, most cysteine substitutions cause classic MFS with a high frequency of lens dislocation, although some patients in our study did not meet the Ghent criteria for diagnosis of MFS [ 9 ] . Amino-acid substitutions not disrupting disulfide bonds may be associated with fibrillinopathies other than MFS, although mutations in the calcium-binding consensus sequence have been reported in individuals with classic MFS [ 5 10 11 12 ] . It is clear from the studies reported so far, that genotype-phenotype correlations are not straight-forward for FBN1 mutations.

  • Moreover, the 1B4 mutation reveals a mechanism by which U3 gene trap vectors can be expressed without disrupting cellular gene expression and suggests ways to improve the vectors for gene trap mutagenesis.

  • Disrupting this "landmarks plot," the FBI in June 1993 arrested Rahman and various confederates.

  • This model predicts that Siah1a association produces its effect by disrupting the interaction of CaM with the group I mGluRs.


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