Example sentences for: disrupting

How can you use “disrupting” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This model predicts that Siah1a association produces its effect by disrupting the interaction of CaM with the group I mGluRs.

  • His job consists of paying off tribal chiefs to prevent them from disrupting pumping operations.

  • Doerflinger happily argued that by demonstrating other ways of deriving stem cells, the new experiments had proved that the cloning of whole embryos could be banned, as Catholic scholars have proposed, without disrupting biotech research.

  • A gene is “knocked out” (KO) by homologous recombination of a disrupting piece of DNA within that gene.

  • For example, exon-skipping mutations in the central region of the gene, exons 24-32, cause severe phenotypes or neonatal presentations [ 8 ] . But there are exceptions, only four of the many other mutations in this region cause severe phenotypes, while one mutation predicted to lead to skipping of exon 24 was found in a patient with classic MFS [ 5 ] . In contrast, most cysteine substitutions cause classic MFS with a high frequency of lens dislocation, although some patients in our study did not meet the Ghent criteria for diagnosis of MFS [ 9 ] . Amino-acid substitutions not disrupting disulfide bonds may be associated with fibrillinopathies other than MFS, although mutations in the calcium-binding consensus sequence have been reported in individuals with classic MFS [ 5 10 11 12 ] . It is clear from the studies reported so far, that genotype-phenotype correlations are not straight-forward for FBN1 mutations.


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