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Example sentences for: disrupted
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TN-C knockout mice show decreased accumulation of FN in wounded tissue and this decrease has been hypothesized to be due to disrupted incorporation on FN into the matrix in the absence of TN-C [ 32 33 ] . Therefore, our observation that inhibition of cCAF-induced TN production decreases the accumulation of FN supports the findings in the knockout mice.
3A; p < 0.05), indicating that regions of disrupted white matter geometry are inhibitory to neurite growth.
Such truncation of the Neo gene disrupted its ability to encode resistance to G418 confirming the results of Beck et al (data not shown) [ 16].
Warned by the CIA that the disrupted Jordanian plot was probably part of a larger series of attacks intended for the millennium, some possibly involving chemical weapons, the Principals Committee met on the night of December 8 and decided to task Clarke's Counterterrorism Security Group (CSG) to develop plans to deter and disrupt al Qaeda plots.
The precise biological role of SLS in streptococcal infections remains controversial [ 7 ] . The original analysis of the sagA gene demonstrated that inactivation of the gene encoding the polypeptide component of SLS rendered the organism less virulent in a dermonecrotic mouse model [ 3 ] . In a related series of studies, Li et al also isolated a mutant that not only lacked SLS activity but also affected other phenotypes [ 4 ] . The additional phenotypes included surface M and M-related protein as well as the secreted cysteine protease, streptococcal pyrogenic exotoxin B, SpeB [ 4 ] . The disrupted gene was termed pel (pleotrophic effect locus).
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