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Example sentences for: dhps

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Although it has been indicated that no DHPS could be detected in archaeal genomes [ 25], orthologs of bacterial DHPS are readily identifiable in all archaea; this enzyme is missing only in animals and in several intracellular bacterial pathogens, such as Rickettsia prowazekii, spirochetes and mycoplasmas (COG0294 in the database of Clusters of Orthologous Groups of proteins (COGs)) [ 26].
An analysis using ORF, a program developed to recognize folds by comparing predicted secondary structures of proteins ([ 27]; we are unaware of a published detailed description of this method), identified MJ0301 as a homolog of DHPS, although, given the low sequence similarity, a convergent origin of the relationship between MJ0301 and DHPS was deemed likely (there seems to be a terminological confusion involved here, but we are quoting the results of the original computational analysis of this protein as they have been presented).
In contrast, DHPS activity (albeit relatively low) was shown in vitro for the partially purified MJ0301 protein [ 25].
In four of the six cases described (CysRS, DHPS, TS and MP), such evidence was obtained by computational methods.
Some archaeal species, including Thermoplasma and Halobacterium, have the bacterial-type DHPS, which was probably acquired by horizontal gene transfer and displaced the original archaeal version.