Words similar to dhprs
Example sentences for: dhprs
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Furthermore, the incomplete inactivation of the γ 1 null Ca 2+current resembles that observed in ts A201 cells expressing DHPRs specifically lacking γ 1 and using a 3-second inactivation protocol [ 22].
Thus we are certain that the EC coupling expressed by fs-α 1S is mechanistically similar to control skeletal-type EC coupling but limited in magnitude by a comparatively lower density of functional DHPRs that are assembled in cells expressing fs-α 1S . It is conceivable that the functional integrity of the fragmented α 1S protein is maintained in part by the β subunit of the DHPR which spans both halves of the α1 pore subunit by binding to the I-II loop and the C-terminus [ 35 36 ] . Consistent with this explanation, we failed to detect EC coupling recovery when fs-α 1S was expressed in β1-null myotubes.