Example sentences for: degrade

How can you use “degrade” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The other non-null recBCD mutants ( recC1001, recC1002, recC1003, recC1004, recC2145, recB2154 , and recB2155 ) are all nuclease positive [ 21 22 ] . They would be expected to degrade the huge linears.

  • For example, Cul1 mutations in mice result in the accumulation of the SCF substrate cyclin E but not of p27 another well characterized SCF substrate [ 32 ] . Among all of the substrates targeted for degradation by SCF in S. cerevisiae , it is the failure to degrade Sic1 that underlies the G1 arrest in cdc53 mutants [ 3 ] [ 4 ] . Thus, different substrates of the SCF appear to have particularly high dependence on SCF activity in different biological contexts.

  • Mutations in the E2 enzyme Cdc34 or in any of the SCF Cdc4components (Cdc53/Cul1, Skp1 and Cdc4) arrest cells at the G1/S transition because of a failure to degrade the cyclin-dependent kinase (CDK) inhibitor Sic1 [ 3 ] [ 4 ] . In a wild-type situation, G1 cyclin/CDK complexes phosphorylate Sic1 at the end of G1.

  • After being engulfed, the bacterium secretes virulence factors to degrade the phagosome.

  • This study demonstrates that monocytes and fibroblasts in co-culture can release MMPs and degrade extracellular matrix.


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