Example sentences for: degrade

How can you use “degrade” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • CES1 is expressed in mature monocytes and macrophages, and is involved in the degradation of xenobiotics [ 15 ] . MMP2 or MMP15, or both, are connective tissue degrading enzymes [ 16 ] . A hypothetical role for MMP2 and MMP15 in the Blau syndrome is that aberrant expression of MMP2 and MMP15 could inappropriately degrade connective tissue, which, in turn, could release stored cytokines and inflammatory mediators, such as tumor necrosis factor α and interleukins and potentially expose neo-epitopes.

  • In both cell lines, DFF45 began to significantly degrade by 1 h after treatment.

  • RNA was further treated with bovine DNAse I (Sigma) to degrade impurity DNA.

  • Our previous work has focused on the pathways by which IL-1β induces several members of the family of matrix metalloproteinases (MMPs), enzymes that are active at neutral pH and that collectively degrade the various components of the extracellular matrix.

  • Mutations in the E2 enzyme Cdc34 or in any of the SCF Cdc4components (Cdc53/Cul1, Skp1 and Cdc4) arrest cells at the G1/S transition because of a failure to degrade the cyclin-dependent kinase (CDK) inhibitor Sic1 [ 3 ] [ 4 ] . In a wild-type situation, G1 cyclin/CDK complexes phosphorylate Sic1 at the end of G1.


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