Words similar to degradative
Example sentences for: degradative
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These large spots were reminiscent of recently described aggresomes, accumulations of misfolded protein that are being targeted for proteasome-dependent degradation [ 17 18 ] . This observation suggested the possibility that intracellular localization of sα i2 may reflect targeting to a proteasome-dependent degradative pathway.
Ferrate(VI) is a very strong oxidizing agent and will readily oxidize many organic molecules in aqueous solution [ 19 20 21 ] . High oxidation power selectivity and by-production of non-toxic Fe(III) make potassium ferrate(VI) an environmentally friendly oxidant for removal of industrial contaminants from natural waters [ 22 ] . We confirmed this degradative activity of ferrate using 2,4,6-trinitrotoluene (TNT), though a mixture of dodecane and hexadecane, as might be found within microbial membranes, was not degraded by ferrate(VI) (Figures 1and 2).
Thus, the results of Figure 7are consistent with the proposal that the intracellular localization of sα i2 is due to its targeting to a degradative pathway, a pathway shared by α i2 .
In Xenopus oocytes, however, some work has suggested that heat shock-dependent accumulation of AppppN is largely due to inactivation of degradative enzymes [ 30 ] .
Although little is known regarding degradative pathways for G proteins, sα i2 and other mutants ( e.g., α i2 A327S) may be valuable tools for defining such pathways.
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