Example sentences for: degrading

How can you use “degrading” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Second strand cDNA is synthesized by degrading the poly(A) +RNA strand with RNase H, followed by second strand synthesis with E. coli DNA polymerase I. Amplified antisense RNA (aRNA) is obtained from in vitro transcription of the double-stranded cDNA (ds cDNA) template using T7 RNA polymerase.

  • However, testing for decrease in PA activity showed that this enzyme is not activated even in the controls, therefore, it is unlikely that this would be a major mechanism involved in degrading FN.

  • Genes encoding proteins involved in moving, modifying, storing and degrading proteins constituted the third largest group (12%) in the stress cDNA collection.

  • Over the last decade, RNA interference (RNAi), mediated by short interfering double-stranded RNA molecules (siRNA or dsRNA), has been gradually recognized as a major mechanism of post-transcriptional gene silencing (PTGS) in species as diverse as plants, Drosophila, and C. elegans [ 1 ] . Recently, 21-nucleotide long dsRNA molecules corresponding to specific mRNA sequences, when introduced into mammalian cells in culture, have been shown to be highly effective in degrading the cognate mRNAs and thus abrogating the expression of the corresponding proteins [ 2 ] . Although the exact mechanism of PTGS is currently unknown and is an area of intense research, the successful use of this phenomenon in cultured mammalian cells has raised the exciting prospect that it can be used as a simple strategy for phenotypic ablation of mammalian gene function ex vivo without the time-consuming and expensive construction of transgenic animals.

  • People who are not judges can do little harm beyond mildly degrading the language and annoying linguistic purists.


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