Example sentences for: degradation

How can you use “degradation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In one type, silencing results from a block in mRNA synthesis (transcriptional gene silencing [TGS]); in the second type, silencing results from mRNA degradation (posttranscriptional gene silencing [PTGS]) (Figure 1).

  • A previous study showed that kelatorphan in addition to blocking the degradation of the exogenous peptide by suppressing the aminopeptidase activity, markedly increased the spontaneous release of endogenous Met-enkephalin in vivo and in vitro ( 16).

  • In any case, our finding shows that when dCul1 function is reduced, the normal pattern of E2F degradation in S phase is disrupted, leading to inappropriate persistence of E2F.

  • Deubiquitinases, such as Rpn11, serve as proofreading devices for reversal of fortune at various stages of the process, right up to the final step before irreversible degradation by the proteasome.

  • The increased expression of βTrCP/slimb [ 26 ] and the ubiquitin conjugating enzyme Ubc4/5E2 (Figure 1), both involved in degradation of β-catenin [ 27 ] , could act as a negative feedback loop in Wnt signaling.


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