Example sentences for: dbf

How can you use “dbf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Transcription has been postulated to play an important role in triggering exit from mitosis [ 20 ] . For example, Dbf2, a protein kinase that promotes exit from mitosis, is associated with the CCR4 transcription regulatory complex [ 21 ] . In addition, the Swi5 transcription factor activates SIC1 expression during late anaphase, and both sic1Δ and swi5Δ are synthetically lethal with

  • The most parsimonious model that unifies all of these observations is as follows: Tem1 functions upstream of Cdc15, which in turn activates the Dbf2-Mob1 protein kinase complex [ 46 47 48 49 ] . Together with Cdc5, these proteins dislodge Cdc14 from nucleolar Net1.

  • net1 tab 2-1bypassed cdc15Δ, tem1Δ, dbf2Δ dbf20Δ, mob1Δ, but not cdc14Δ (Figure 4A; [ 15 ] ). In addition, it bypassed cdc5Δ with negligible (1000-10,000 fold lower) efficiency (Fig.

  • , submitted), Mob1 binds an essential protein kinase involved in spindle pole body duplication [ 27 ] , and Tem1, Cdc15, Dbf2, and Mob1 have all been implicated in cytokinesis ( [ 28 29 30 31 ] ; reviewed in [ 1 ] . The tab mutants provide a unique opportunity to address this issue.

  • This explanation is unlikely to account fully for Cdc5's role in exit from mitosis, however, because (1) overexpression of Cdc5, but not Dbf2/Mob1, provoked ectopic release of Cdc14 from the nucleolus; and (2) the Dbf2/Mob1 kinase complex is at least partially activated and is correctly localized to the spindle pole body in 50% of cdc5 cells at the nonpermissive temperature [ 16 17 ] .


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