Words similar to dbf

Example sentences for: dbf

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The net1 tab 2-1mutation efficiently bypassed tem1Δ, cdc15Δ, dbf2Δdbf20Δ, and mob1Δ, consistent with the notion that the sole essential function of all these genes is to inhibit Net1.
Tem1 recruits Cdc15 to the spindle pole body, which in turn recruits and phosphorylates the Dbf2/Mob1 protein kinase complex, thereby switching it on [ 2 14 15 16 17 ] . The Tem1-signaling pathway eventually triggers disassembly of the RENT complex, enabling the release of Cdc14 (and a portion of Sir2) from Net1.
Identified components of the MEN include Tem1 (a GTP-binding protein), Lte1 (a putative guanine nucleotide releasing factor), Nud1 (a spindle-pole-body protein), Cdc15 (a protein kinase), Dbf2/Mob1 (a protein kinase complex), Cdc5 (a Polo-like protein kinase), and Cdc14 (a protein phosphatase).
net1 tab 2-1bypassed cdc15Δ, tem1Δ, dbf2Δ dbf20Δ, mob1Δ, but not cdc14Δ (Figure 4A; [ 15 ] ). In addition, it bypassed cdc5Δ with negligible (1000-10,000 fold lower) efficiency (Fig.
The net1(19m') allele also showed a synthetic growth defect when combined with dbf2-1 . These observations imply that some of the residues mutated in net1(19m') represent in vivo phosphorylation sites that influence the MEN-dependent release of Cdc14 during anaphase.