Example sentences for: dbd

How can you use “dbd” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The NR family contains two related ERs (ERα and ERβ) that conform to the typical three domain NR structure and share extensive sequence homology in the DBD and LBD region [ 20 21 ] . Analysis of the function of the individual ERs in mouse knockout models suggests that the major proliferative effects of estrogen are mediated by ERα and not by ERβ, which seems to play an inhibitory role in proliferation in some studies [ 22 23 ] . The ligand-binding properties of the ERs are different, with ERβ often exhibiting stronger binding to plant-derived phytoestrogens [ 24 ] . More importantly, the ERs exhibit isoform-specific effects on gene expression.

  • To examine interactions between ERβ and N-CoR in mammalian cells we performed two-hybrid assays using a GAL4 DBD/N-CoR C-terminus fusion protein as bait and a VP16-ERβ LBD fusion as the prey.

  • DBD DNA Binding Domain

  • 7, DBD + 154-257).

  • 1B, DBD), which still targeted to peri-centromeric chromatin, did not prolong G1 (Fig.

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