Words similar to dbp

Example sentences for: dbp

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Deletion of the cryptochromes disinhibits the transcriptional activation of CLOCK:BMAL1 and NPAS2:BMAL1 target genes, resulting in increased levels of their transcripts in the SCN, liver, and retina [ 20 23 25 ] . We assayed the expression in the brain of three genes that are known targets of cryptochrome mediated transcriptional inhibition: albumin D-binding protein ( dbp [ 26 ] ), period (per)1 , and per2 [ 20 23 27 ] , in the middle of the daily light period.
After 4 h of recovery sleep, per1 , 2 and dbp expression returned to the normal levels for that time of day (ZT10; Figure 5A).
Albumin D-binding protein ( Dbp ) is a transcription factor whose expression is under the direct transcriptional control of CLOCK:BMAL1 [ 26 ] . Deletion of the dbp gene, which results in a shortening of the circadian period [ 35 ] , also results in decreased sleep consolidation and NREMS delta power [ 36 ] .
Both per1 and per2 mRNA levels were higher immediately after SD compared to controls, cry1,2 expression did not change, and dbp mRNA decreased significantly (Figure 5A).
Messenger RNA levels for per1 , 2 , cry1 , 2 , and dbp were quantified by RT-PCR in three brain areas (cerebral cortex, basal forebrain, and hypothalamus) from C57BL/6 mice that were sacrificed immediately after 6 h of SD or after 4 h of recovery sleep (ZT10).