Example sentences for: dbp

How can you use “dbp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The high per levels in cry1,2 -/-mice and the low per levels in clock mutant mice [ 26 47 ] correlate with their contrasting sleep phenotype (see above; [ 34 ] ). In this context, the sleep abnormalities in dbp -/-mice might also be related to a reduction in per expression since, at least in vitro , DBP can amplify the CLOCK:BMAL1-induced transcription of per [ 48 ] , but it is not known whether per transcript levels are altered in dbp -/-mice.

  • From each animal, quantitative real-time PCR determinations of 5 target genes ( cry1,2, per1,2 , and dbp ) and a reference cDNA (glyceraldehyde-3-phosphate dehydrogenase, g3pdh ) were made from the cortex, basal forebrain, and hypothalamus (primer/probe sequences available upon request).

  • Messenger RNA levels for per1 , 2 , cry1 , 2 , and dbp were quantified by RT-PCR in three brain areas (cerebral cortex, basal forebrain, and hypothalamus) from C57BL/6 mice that were sacrificed immediately after 6 h of SD or after 4 h of recovery sleep (ZT10).

  • Both per1 and per2 mRNA levels were higher immediately after SD compared to controls, cry1,2 expression did not change, and dbp mRNA decreased significantly (Figure 5A).

  • Albumin D-binding protein ( Dbp ) is a transcription factor whose expression is under the direct transcriptional control of CLOCK:BMAL1 [ 26 ] . Deletion of the dbp gene, which results in a shortening of the circadian period [ 35 ] , also results in decreased sleep consolidation and NREMS delta power [ 36 ] .


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