Example sentences for: dbdgd

How can you use “dbdgd” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In addition to the DbDGD motif, which is located in the loop between strands 5 and 6, several residues are conserved between these polymerase families (Fig.

  • One of these corresponds to the catalytic, metal-coordinating domain, containing the DbDGD motif, in the β' subunit (residues: 626-750 of pdb id:1iw7 chain D), whereas the other one corresponds to the conserved core domain of the β subunit (residues:673-994 of pdb id: 1iw7 chain C).

  • The high-scoring segment pairs (HSPs) detected in these searches aligned the highly conserved region of the RDRPs between the predicted strands 18 and 20, including the DbDGD motif, with the portion of the DDRP β' subunit sequence, which contains the metal-chelating active site, with a similar conserved motif, DxDGD.

  • This domain adopts the DPBB fold, in which the signature DbDGD motif, shared by RDRP and DDRP, is ensconced in the insert between the ultimate and penultimate β-strands.

  • Closely spaced acidic residues that coordinate divalent cations are characteristic of the active sites of most nucleic acid polymerases, in spite of the fact that they belong to several unrelated structural folds [ 9 13 14 17 28 29 59 ] . Given that the DbDGD motif is the only set of closely spaced acidic residues shared by the RDRPs and the YRHs, it is likely to form part of the nucleotidyltransferase active site of these enzymes.


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