Example sentences for: cyclooxygenase

How can you use “cyclooxygenase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Assessment of cyclooxygenase activity

  • With this inhibition, new production of cyclooxygenase products is blocked.

  • Ibuprofen is a reversible, short-acting cyclooxygenase inhibitor, which particularly blocks the synthesis of thromboxane.

  • Regular use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been consistently associated with reduced risk of colorectal cancer and adenoma [ 1 2 3 4 ] , and there is some evidence for a protective effect for other types of cancer [ 5 6 7 8 9 ] . It is widely thought that the mechanism by which these drugs affect cancer risk is through the inhibition of the cyclooxygenase (COX) enzymes: the constitutively expressed COX-1 and the induced (in most tissues) COX-2 [ 10 ] . By inhibiting these enzymes, NSAIDs can inhibit prostaglandin synthesis, enhance cellular immune response, or induce of apoptosis, all of which have been postulated to be involved in carcinogenesis [ 11 12 13 ] .

  • It has been indicated that the pathway of cyclooxygenase products, such as TxB 2 and PGE 2 , increases in many endotoxic shock models and plays an important role in a number of pathophysiological events [ 21 27 ] .


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