Words similar to cyclooxygenase
Example sentences for: cyclooxygenase
How can you use “cyclooxygenase” in a sentence? Here are some example sentences to help you improve your vocabulary:
The cyclooxygenase pathway and NSAIDs have been implicated in pancreatic carcinogenesis, as elevated levels of COX-2 mRNA and protein have been detected in pancreatic carcinomas relative to histologically normal cells [ 14 15 16 17 18 19 ] . Further, both aspirin [ 20 21 22 ] and other NSAIDs [ 19 ] have been shown to inhibit pancreatic cancer cell proliferation and induce apoptosis in vitro . Recent studies have also reported an association between oncogenic ras and COX-2 expression [ 23 24 ] . Since pancreatic tumors tend to exhibit a high frequency of K- ras mutations [ 25 ] , the relationship between the K- ras oncogene and COX-2 should be explored further in vivo.
Thus, it appears that ibuprofen has no effect on secreted cyclooxygenase products, as it inhibits the cyclooxygenase enzyme.
It has been indicated that the pathway of cyclooxygenase products, such as TxB 2 and PGE 2 , increases in many endotoxic shock models and plays an important role in a number of pathophysiological events [ 21 27 ] .
Assessment of cyclooxygenase activity
With this inhibition, new production of cyclooxygenase products is blocked.