Example sentences for: cycloheximide

How can you use “cycloheximide” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Along these lines, when the aminogylcosides (kanamycin, hygromycin B, paromycin and neomycin) due to their ability to inhibit protein synthesis by affecting ribosomal fidelity, or puromycin because of its competing ability with tRNAs for binding on the large ribosomal subunit, or cycloheximide which inhibit the large ribosomal subunit by preventing ribosomal movement along the mRNA, were used in active HIV-1 infection, it was found that both cycloheximide and puromycin produced the greatest decrease in HIV-1 inhibition, presumably by inhibiting the large subunit of the ribosome [ 41 ] .

  • Subsequent to purification, T cells were replaced in culture for 36-40 hr prior to restimulation with 1 nM IL-2, and/or 10 μg/ml cycloheximide.

  • In addition, 10 μg/mL cycloheximide (CHX) was included to block protein synthesis, so that only immediate/early IL-2-regulated genes were detected.

  • Interestingly, Clb2 was rapidly and efficiently degraded upon reversal of the cdc15-2 block regardless of whether cycloheximide was present (Figure 1) although both cytokinesis and cell separation require protein synthesis [ 42 ] . This observation suggests that the exit from mitosis in budding yeast may be controlled by mechanisms fundamentally similar to those employed by animal cells, which proceed through mitosis with highly condensed, transcriptionally silent chromosomes.

  • In the absence of cycloheximide, Sic1 accumulated and Clb2 disappeared as cells exited mitosis (Figure 1, lanes 1-4).


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