Words similar to cycloheximide

Example sentences for: cycloheximide

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In contrast, cycloheximide did not block induction of target genes by BMP (Figure 4), the mechanism of which does not involve protein accumulation [ 12 ] . These findings underscore the importance of β-catenin protein elevation in the response to Wnt.
The medium was then changed with readdition of pon A or an equal volume of ethanol and the protein synthesis inhibitor cycloheximide (100 μg/ml, Sigma) was added.
Cochran and Stiles were among the first to use differential cloning methods to identify PDGF-regulated genes in fibroblasts [ 26 ] . These investigators focused on the expression of immediate/early PDGF-stimulated genes, by activating the cells in the presence of inhibitors of protein synthesis such as cycloheximide, thereby preventing the expression of secondary genes.
Interestingly, Clb2 was rapidly and efficiently degraded upon reversal of the cdc15-2 block regardless of whether cycloheximide was present (Figure 1) although both cytokinesis and cell separation require protein synthesis [ 42 ] . This observation suggests that the exit from mitosis in budding yeast may be controlled by mechanisms fundamentally similar to those employed by animal cells, which proceed through mitosis with highly condensed, transcriptionally silent chromosomes.
Protein synthesis was inhibited by cycloheximide in control cells and in cells pretreated with MIB for 72 h.