Example sentences for: cyclin

How can you use “cyclin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We also determined the expression of the S phase marker cyclin A in these cells.

  • 1B, relative phosphorylation levels of RARα decreased by 3 fold, similar to the reduction in cyclin H and cdk7 expression.

  • 9-nitropaullone, the most potent member of a novel class of the paullone CDK inhibitor family, inhibits CDK1/cyclin B at 10-fold lower concentrations than flavopiridol and roscovitine [ 22, 23, 24].

  • , less than 100 nM) can selectively suppress HIV-1 transcript elongation without altering cellular transcripts in cell types of various lineages, including podocytes [ 7 29 30 ] . Cyclin D 1 transcript levels were followed before, during, and after treatment of confluent wild-type or HIV-1 infected podocytes with 50 nM flavopiridol, a dose that suppresses HIV-1 transcription by 70% [ 7 ] . Analysis of HIV-1, cyclin D 1 , and glyceraldehyde-3-phosphate dehydrogenase (G3PDH) transcript levels in podocytes treated with flavopiridol for 2 days, followed by drug washout for 1 day, showed that cyclin D 1 expression paralleled HIV-1 expression in infected podocytes before, during and after suppression of HIV-1 genes (Figure 4).

  • For example, Pop1p is involved in the control of the RNA levels of the cyclin Cig2p [ 33 ] . While it is unclear whether this effect is mediated at the level of transcription or mRNA stability, the budding yeast F-box protein Met30p was recently shown to regulate the ubiquitylation and activity, but not degradation, of the transcription factor Met4p [ 34 ] . In addition, pop1 mutants display an increased rate of chromosome loss, a phenotype that is not easily explained by accumulation of Rum1p and Cdc18p [ 23 ] . Finally, pop1 mutants are sensitive to UV irradiation, whereas pop2 mutants are not (D.


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