Words similar to cyclin-dependent

Example sentences for: cyclin-dependent

How can you use “cyclin-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:

First, we utilized the small molecule cyclin-dependent kinase inhibitor, flavopiridol, which at low concentrations (e.g.
Under conditions favoring proliferation, the phosphorylation of pRB via cyclin-dependent kinases (CDKs) in mid-to-late G 1 phase results in liberation of E2F and other pRB-bound transcription factors, which then activate the transcription of S-phase genes [ 19 ] . In late M phase, pRB returns to its growth suppressive, hypophosphorylated form due to the action of a pRB-directed protein phosphatase belonging to the type 1 class of serine/threonine protein phosphatases [ 11 20 21 ] .
Flavopiridol is a member of the growing family of cyclin-dependent kinase (CDK) inhibitors that have varying activities against the multiple CDK family members (CDK1, CDK2, CDK4, CDK6 and CDK7) by competitively blocking their ATP-binding pocket [ 4, 5, 6, 7, 8].
Cdc2, a catalytic subunit of cyclin-dependent kinases, is required for both the G1-to-S and G2-to-M transitions.
Genetic experiments suggested that degradation of Rum1p depends on the Pop1p and Pop2p F-box proteins [ 18 20 ] , but also requires phosphorylation of Rum1p on serine 58 and threonine 62 by cyclin-dependent kinase (CDK) [ 21 ] . Thus, phosphorylated Rum1p may be a substrate for SCF Pop1p-Pop2p-mediated polyubiquitylation.